CONFERENCE SCHEDULE
* April 23-27, 2012

 

MONDAY, April 23th

9:30 – 11:00 am REGISTRATION

10:45 – 11:00 am Opening Remarks

11:00 – 11:30 am KEYNOTE ADDRESS – Melissa Hines (Cambridge, UK) – Gender development and behavior

 

Organogenesis

Session Chair: Blanche Capel (Durham, NC)

 

11:30 – 11:45 pm – Neil Gemmell Investigating the genetic basis of sequential hermaphroditism in bluehead wrasse

11:45 – 12:00 pm - Serge Nef Absence of insulin and IGF1 receptors affects gonadal differentiation and adrenal development in mice

12:00 – 12:15 pm – Sergei Tevosian Control of sexual development by GATA transcription factors

12:15 – 12:30 pm – Stefan Bagheri-Fam Fgfr2lllC is required for testis determination but is dispensable for subsequent testis cord differentiation and spermatogenesis

 

LUNCH

 

2:00 – 2:15 pm – Andrew Pask Desert hedgehog is a mammal-specific gene expressed during testicular and ovarian development in a marsupial

2:15 – 2:30 pm – Humphrey Yao Synergistic and cell type specific action of TGFß family members in cell fate determination and proliferation of mouse fetal testis

2:30 – 2:45 pm – Yuichi Shima Functional characterization of fetal Leydig cells by cell-specific disruption of Ad4BP/SF-1 gene

2:45 – 3:00 pm – Chang Liu Migrating GLI1-expressing cells from the mesonephros contribute to ovarian theca cell lineage

3:00 – 3:15 pm – Yoshi Kanai Spatiotemporal changes in sexual bipotentiality and plasticity of granulosa cells in developing mouse ovaries

 

BREAK


3:45 – 4:00 pm – Joan Jorgensen IRBX cluster genes are essential for oocyte integrity and follicle health during oocyte maturation

4:00 – 4:15 pm – Allison Stewart Development of the mouse oviduct

4:15 – 4:30 pm – Gen Yamada ß-catenin regulates cell proliferation via FoxA2 during during endometrial hyperplasia formation

4:30 – 4:45 pm – Paul Gradie A novel mouse model for severe congenital hypospadias

4:45 – 5:00 pm – Shengui Zheng Prenatal inactivation of androgen receptor activity feminizes external genitalia but masculinizes brain development

5:00 – 5:15 pm Monika Ward Only two Y chromosome genes are needed for successful reproduction

5:15 – 5:30 pm Makoto Tachibana The histone demethylase Jmjd1a controls sex determination via activating Sry expression

 

6:30 – 10:00 pm WELCOME RECEPTION

 

 

TUESDAY, April 24th

7:30 – 8:00 am REGISTRATION

8:00 – 8:30 am CONTINENTAL BREAKFAST


Sex Determination/Transcriptional Regulation

8:30 – 9:00 am Session Chair – Vivian Bardwell (Minneapolis, Minnesota) – DMRT regulation of sex determination

9:00 – 9:15 am – Maëva Elzaiat Involvement of DMRT1 in XX sex-reversed polled goats.

9:15 – 9:30 am – Ajay Pradhan NFkB and COX-2 signaling in zebrafish sex determination

9:30 – 9:45 am – Michiko Ito Molecular evolution of vertebrate Dmrt1 homologues

9:45 – 10:00 am – Kenichi Kashimada Antagonistic regulation of Cyp26b1 by transcription factors Sox9/Sf1 and Foxl2 during gonadal development in mice


BREAK


10:30 – 11:00 am - Invited talk – Vincent Harley (Melbourne, Australia) – Molecular mechanisms of sex determination

11:00 – 11:15 am – Anirudh Natarajan Fine-time transcriptome analysis identifies regulatory interactions in the murine gonad

11:15 – 11:30 am –Danielle Maatouk Using DNaseI-Seq to identify genome-wide patterns of nucleosome depletion in a single cell lineage of the fetal mouse testis

11:30 – 11:45 am – Ramji Bhandari Genome wide analysis of downstream targets of Sry and Sox9

11:45 – 12:00 pm – Valerie Arboleda Protection from C57BL/6-Ypos sex reversal is conferred by a POSa-specific enhancer of Sox9


LUNCH


Sex Determination/Differentiation

1:30 – 2:00 pm Session Chair, Michael Clinton (Edinburgh, Scotland) – Sex determination and differentiation in chicken

2:00 – 2:15 pm – Katie Ayers. Identification of novel W-linked genes and potential sex determinants in the chicken using RNA sequencing

2:15 – 2:30 pm – Justin Chue FOXL2 and ovarian differentiation in the chicken embryo

2:30 – 2:45 pm – Deborah Toledo Flores Sex without sox? Sox3 and Dmrt genes in monotremes.

2:45 – 3:00 pm – Ayaka Yano New insights into sex determination in salmonids


BREAK


3:30 – 4:00 pm – Invited speaker – Turk Rhen (Grand Forks, North Dakota) – Sex determination mechanisms in reptiles

4:00 – 4:15 pm – Lisa Schwanz Evolutionary transitions between GSD and TSD without crossing a fitness barrier

4:15 – 4:30 pm – Nicole Valenzuela Wild turtle sex

4:30 – 4:45 pm – Michael Czerwinski Whole transcriptome analysis in Trachemys scripta elegans sex determination

4:45 – 5:00 pm – John Postlethwait Genetic mechanisms of sex determination in zebrafish


 

WEDNESDAY, April 25th

8:00 – 8:30 am CONTINENTAL BREAKFAST


Sex Chromosomes Evolution, Genetics, and Genomics

8:30 – 9:00 am Session Chair, Tariq Ezaz (Canberra, Australia) – Evolution of vertebrate sex chromosomes

9:00 – 9:15 am Denis O’Meally What makes some chromosomes so good at sex?

9:15 – 9:30 am Frederic Veyrunes A novel sex determination system in a close relative of the house mouse: XY females in Mus minutoides

9:30 – 9:45 am Christine Dreyer Genetic mapping and genomic analysis of guppy sex chromosomes

9:45 – 10:00 am Ikuo Miura Evolution of gonadal sex differentiation mechanisms from sex hormone dependent to independent in frog

10:00 –10:15 am Daleen Badenhorst Sex chromosome evolution and new karyotype data of Apalone spinifera (Testudines; Tryonchidae).



BREAK



10:45 – 11:15 am Session Chair/Invited talk – Manfred Schartl (Würzburg, Germany) – Evolution of sex determination mechanisms in fish

11:15 – 11:30 am – Ruth Phillips Evidence for sexually antagonistic genes on the Y chromosome of Pacific salmon

11:30 – 11:45 am – Satoshi Hamaguchi Sex determining gene is not conserved in Oyzias fishes with homomorphic chromosomes

11:45 – 12:00 pm – Kiyoshi Kikuchi The sex determining loci in fugu and its related species

12:00 – 12:15 am – Taijun Myosho A duplicated copy of Gsdf on the Y chromosome is the prime candidate of the sex determining gene in Oryzias pectoralis

12:15 – 12:30 pm – Ching-Fong Chang An epigenetic switch mediates the determination of ovary formation in the protandrous black porgy fish.


AFTERNOON FREE


6:00 – 10:00 pm POSTER SESSION

 


 

THURSDAY, April 26th

8:00 – 8:30 am CONTINENTAL BREAKFAST


Sex Determination of the Germ Line and Soma Interactions

8:30 – 9:00 am Session Chair/invited speaker - Josephine Bowles (Brisbane, Australia) – Retinoid regulation of germ cell development

9:00 – 9:15 am – Cathryn Hogarth Retinaldehyde dehydrogenase activity is required for Stra8 expression and meiotic progression in the embryonic ovary

9:15 – 9:30 am – Marie-Christine Chaboissier From early gonadal development to sex reversal: the different roles of Rspo1 and Sox9

9:30 – 9:45 am – Nick Warr Identification of a novel mouse autosomal testis-determining gene in the Map3K4 pathway

9:45 – 10:00 am – Dagmar Wilhelm The role of miRNAs in mammalian sex determination



BREAK



10:30 – 11:00 am – Invited speaker – Kellee Siegfried (Boston, Massachusetts) – Genetics of sexual development in zebrafish

11:00 – 11:15 am – Laszlo Orban Polygenic sex determination and conserved features of gonad differentiation in zebrafish

11:15 – 11:30 am – Sok-Keng Tong Regulation of sex-dimorphic development of zebrafish germ cells and gonadal somatic cells.

11:30 – 11:45 am – Rie Goto Number of primordial germ cells is a key factor in zebrafish ovarian differentiation

11:45 – 12:00 pm – Minoru Tanaka The system of sex determination in medaka is largely different from that in mammals



LUNCH



Environmental Effects on Sex Determination, Differentiation and Fertility

2:00 – 2:30 pm Session Chair, Tyrone Hayes (Berkeley, CA) – Environmental effects on amphibian sexual development

2:30 – 2:45 pm – Karina Valdivia Characterization of a masculinizing phenotype in female rainbow trout:gene expression profiles and implication of temperature

2:45 – 3:00 pm – Francesc Piferrer Environmental Influences on fish sex determination and differentiation

3:00 – 3:15 pm – Alexander Quinn Thermosensitivity in molecular pathways of mammalian sex determination

3:15 – 3:30 pm – Arthur Arnold Sex bias in mouse body weight and adiposity caused by sex differences in complement of X and Y genes



BREAK



4:00 – 4:30 pm – Invited speaker – Alan Conley (Davis, California) – Hormonal control of hyena sexual differentiation

4:30 – 4:45 pm – Geneviève Jolivet The rabbit as an efficient model for functional studies of gonadal differentiation

4:45 – 5:00 pm – Vicki Myers-Wallen Genome wide association study and resequencing identifies a region associated with canine testicular and ovotesticular XX DSD

5:00 – 5:15 pm – Marilyn Renfree The network of sex determining genes in a marsupial.


6:30 – 10:00 pm CONFERENCE DINNER


 

FRIDAY, April 27th

8:00 – 8:30 am CONTINENTAL BREAKFAST


Human Disorders of Sexual Development

8:30 – 9:00 am Session Chair/Invited speaker – Eric Vilain (Los Angeles, CA) – Human disorders of sexual development

9:00 – 9:15 am – Stefanie Eggers Whole exome sequencing of a large family with 46, XY DSD complete gonadal dygenesisi and premature ovarian failure revealed a novel three base pair deletion in NR5Ai

9:15 – 9:30 am – Chris Lau SRY and Hirschprung Disease

9:30 – 9:45 am – David Sandberg Stigma as a factor potentially mediating relationships between disorders of sex development and psychological outcomes.

9:45 – 10:00 am Harry Ostrer Signal transduction pathways in mammalian gonadal development



BREAK



10:30 – 11:00 am – Invited speaker - Tsutomu Ogata (Tokyo, Japan) – Molecular genetics of human X chromosome syndromes

11:00 – 11:15 am – Dominique Thépot Diversity of X-inactivation initiation mechanisms in mammals.

11:15 – 11:30 am – Kelly Roeszler Analysis of the Z-linked putative long non-coding RNA, MHM, in avian sex determination.

11:30 – 11:45 am – Maëlle Pannetier Long non-coding RNAs and sex determining gene regulation in ruminents

11:45 – 12:00 pm – Closing Remarks



CONFERENCE ENDS

 



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